Greene's Protective Groups in Organic Synthesis, Fourth Edition

The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence. This new edition incorporates the significant developments in the field since publication of the third edition in 1998, including...

• New protective groups such as the fluorous family and the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines
• New techniques for the formation and cleavage of existing protective groups, with examples to illustrate each new technique
• Expanded coverage of the unexpected side reactions that occur with protective groups
• New chart covering the selective deprotection of silyl ethers
• 3,100 new references from the professional literature

The content is organized around the functional group to be protected, and ranges from the simplest to the most complex and highly specialized protective groups.Content:
Chapter 1 The Role of Protective Groups in Organic Synthesis (pages 1–15):
Chapter 2 Protection for the Hydroxyl Group, Including 1,2? and 1,3?Diols (pages 16–366):
Chapter 3 Protection for Phenols and Catechols (pages 367–430):
Chapter 4 Protection for the Carbonyl Group (pages 431–532):
Chapter 5 Protection for the Carboxyl Group (pages 533–646):
Chapter 6 Protection for the Thiol Group (pages 647–695):
Chapter 7 Protection for the Amino Group (pages 696–926):
Chapter 8 Protection for the Alkyne ?CH (pages 927–933):
Chapter 9 Protection for the Phosphate Group (pages 934–985):
Chapter 10 Reactivities, Reagents, and Reactivity Charts (pages 986–1051):